Cerebellar-Cortex-Granular-Layer-Interneurons-in-the-Macaque-Monkey-Are-Functionally-Driven-by-pone.0082239.s005

Description:

Description: English: spiking activity of different neuronal elements. The movie shows the raw spike trace, instantaneous firing rate (lower traces), the eye position (upper left), and the spikes as they can be observed during a recording session. The soundtrack also reproduces the sound typically heard on an audio monitor. Recordings from 5 cells are shown: (1) a Purkinje cell (notice that complex spikes are clearly audible, and that the cell responded to ocular pursuit), (2) complex spikes recorded in the molecular layer, (3) a mossy fiber, which exhibited a characteristic sharp spike, high-pitch sound, high and regular firing rate and bursting response to saccades, (4) a GLI with a low and regular firing rate. Notice that the firing rate of this GLI decreased during downward eye movement but does not increased during upward eye movement: it followed a typical ‘I’ profile as that shown in Figure 4D–G. Notice also that a ‘hashing’ activity is audible in the background, which indicates the presence of nearby mossy fibers. (5) a GLI with a high and irregular firing rate. Notice that a nearby mossy fiber with hashing activity is also clearly audible, and that the firing rate of this GLI increased during eye movements to the left but does not decrease during eye movement to the right: it follows a typical ‘E’ profile as in Fig. 4A–C. Note: This movie plays well in our windows movie player (run in windows 7), but other movie players may have problems syncing the sound and image. Date: 2013. Source: Movie S1 from Laurens J, Heiney S, Kim G, Blazquez P (2013). "Cerebellar Cortex Granular Layer Interneurons in the Macaque Monkey Are Functionally Driven by Mossy Fiber Pathways through Net Excitation or Inhibition". PLOS ONE. DOI:10.1371/journal.pone.0082239. PMC: 3869689. Author: Laurens J, Heiney S, Kim G, Blazquez P. Permission (Reusing this file): : This file is licensed under the Creative Commons Attribution 4.0 International license.:. You are free: to share – to copy, distribute and transmit the work to remix – to adapt the work Under the following conditions: attribution – You must attribute the work in the manner specified by the author or licensor (but not in any way that suggests that they endorse you or your use of the work). http://creativecommons.org/licenses/by/4.0 CC BY 4.0 Creative Commons Attribution 4.0 truetrue. Provenance: This file was transferred to Wikimedia Commons from PubMed Central by way of the Open Access Media Importer.: .