Image of Streptococcus pyogenes

Description:

Magnified 100x, this 1977 photograph depicted a Petri dish filled with trypticase soy agar medium containing 5% defibrinated sheep's blood, i.e., blood agar plate (BAP). A loop of diluted culture of Streptococcus pyogenes was put into the melted agar (50^oC) just before the blood was added to the melted agar. The melted agar with blood was allowed to solidify, and then incubated at 35^oC for 24 hours in a normal atmosphere. The culture grew subsurface bacterial colonies, one of which was seen here. The characteristic color changes, i.e., a colorless region surrounding each colony in which the red blood cells in the blood agar medium had been destroyed, or "hemolyzed", indicated that these bacteria were indeed beta-hemolytic in nature.

Infection with GAS can result in a range of symptoms:

- No illness

- Mild illness (strep throat or a skin infection such as impetigo)

- Severe illness (necrotizing faciitis, streptococcal toxic shock syndrome)
Created: 1977