Mammillaria guillauminiana is a species of plant in the family Cactaceae.
The cactus is endemic to northwestern Mexico, in Durango and Sinaloa states.[1]
The species grows in desert scrub habitat, in humus between rocks and in shady places, at 1,300–1,800 metres (4,300–5,900 ft) in elevation.[1]
It was classified on the IUCN Red List as extinct in the wild until rediscovered in 2003. It has been reclassified by IUCN as a Data Deficient species.[1]